Doiron Theoretical Neuroscience Group

Prince Edward Island, Canada



G.K. Ocker & B. Doiron. Training and spontaneous reinforcement of neuronal assemblies by spike timing  (In Review)


G. K. Ocker*, Y. Hu*, M.A. Buice, B. Doiron, K. Josić, R. Rosenbaum & E. Shea-Brown. From the statistics of connectivity to the statistics of spike times in neuronal networks. Current Opinion in Neurobiology 46, 109-119, 2017.


C. Huang & B. Doiron. Once upon a (slow) time in the land of recurrent neuronal networks… Current Opinion in Neurobiology 46, 31-38, 2017.


R.J. Caginalp & B. Doiron. Decision dynamics in groups with interacting members, SIAM Journal on Applied Dynamical Systems 16, 1543-1562, 2017.


S.R. Bittner, R.C. Williamson, A.C. Snyder, A. Litwin-Kumar, B. Doiron, S.M. Chase*, M.A. Smith* & B. M. Yu*.  Population activity structure of excitatory and inhibitory neurons.  PLoS one 12, e0181773, 2017.


C. Ly & B. Doiron. Noise-enhanced coding in phasic neuron spike trains. PLoS one 12, e0176963, 2017.


T. Keck, T. Toyoizumi et al. Integrating Hebbian and homeostatic plasticity: the current state of the field and future research directions.  Phil. Trans. R. Soc. B 372, 20160158, 2017.


T. Kanashiro, G.K. Ocker, M.R. Cohen & B. Doiron. The circuit mechanisms of attentional modulation of neuronal variability. Elife, e23978, 2017.


R. Rosenbaum, M.A. Smith, A. Kohn, J.E. Rubin & B. Doiron. The spatial structure of correlated variability in cortical circuits. Nature Neuroscience, 20, 107-114, 2017.

R.C. Williamson, B.R. Cowley, A. Litwin-Kumar, B. Doiron, A. Kohn, M.A. Smith* & B M. Yu*. Scaling Properties of Dimensionality Reduction for Neural Populations and Network Models PLoS Computational Biology (In Press) B. Doiron, A. Litwin-Kumar, R. Rosenbaum, G. Ocker & K. Josic. The mechanics of state dependent neural correlations. Nature Neuroscience 19, 383-393, 2016. A. Litwin-Kumar, R. Rosenbaum & B. Doiron. Inhibitory stabilization and visual coding in cortical circuits with multiple interneuron subtypes. Journal of Neurophysiology 115, 1399-1409, 2016.


2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001
 A. Litwin-Kumar & B. Doiron. Formation and maintenance of neuronal assemblies through synaptic plasticity. Nature Communications, doi: 10.1038/ncomms6319, 2014. R. Rosenbaum & B. Doiron. Balanced Networks of Spiking Neurons with Spatially Dependent Recurrent Connections. Physical Review X 4, 021039, 2014. G.K. Ocker & B. Doiron. Kv7 Channels Regulate Pairwise Spiking Covariability in Health and Disease. Journal of Neurophysiology, 112: 340–352, 2014. B. Doiron & A. Litwin-Kumar. Balanced neural architecture and the idling brain. Frontiers in Computational Neuroscience 8 doi:10.3389/fncom.2014.00056, 2014. R. Rosenbaum, A. Zimnik, F. Zheng, R. Turner, C. Alzheimer, B. Doiron, & J.E. Rubin. Axonal and synaptic failure suppress the transfer of firing rate oscillations, synchrony and information during high frequency deep brain stimulation. Neurobiology of Disease, 62: 86-99, 2014. Z.P. Kilpatrick, B. Ermentrout & B. Doiron Optimizing working memory with heterogeneity of recurrent cortical excitation. Journal of Neuroscience, 33: 18999-19011, 2013. R. Rosenbaum, J.E. Rubin & B. Doiron. Short term synaptic depression and stochastic vesicle dynamics reduce and reshape neuronal correlations. Journal of Neurophysiology, 109: 475-484, 2013. A. Litwin-Kumar & B. Doiron. Slow dynamics and high variability in balanced cortical networks with clustered connections. Nature Neuroscience. 15: 1498-1505, 2012. A. Litwin-Kumar, M.J. Chacron & B. Doiron. The spatial structure of stimuli shapes the timescale of correlations in population spiking activity. PLoS Computational Biology 8, e1002667, 2012. R. Rosenbaum, J.E. Rubin & B. Doiron. Short term synaptic depression imposes a frequency dependent filter on synaptic information transfer. PLoS Computational Biology, 8, e1002557, 2012. R.M. Leao, S. Li, B. Doiron & T. Tzounopoulos. Diverse levels of an inwardly rectifying potassium conductance generate heterogeneous neuronal behavior in a population of dorsal cochlear nucleus pyramidal neurons. Journal of Neurophysiology, 107, 3008-3019, 2012 A. Polk, A. Litwin-Kumar & B. Doiron. Correlated neural variability in persistent state networks. Proceedings of the National Academy of Sciences, 109, 6295-6300, 2012. C. Ly, J.W. Middleton & B. Doiron. Cellular and circuit mechanisms maintain low spike co-variability and enhance population coding in somatosensory cortex. Frontiers in Computational Neuroscience 6 doi: 10.3389/fncom.2012.00007, 2012. J.W. Middleton, C. Omar, B. Doiron & D.J. Simons. Neural correlation is stimulus modulated by feedforward inhibitory circuitry. Journal of Neuroscience, 32, 506-518, 2012. A. Litwin-Kumar, A-M. M. Oswald, N.N. Urban & B. Doiron. Balanced synaptic input shapes the correlation between spike trains. PLoS Computational Biology, 7: doi:10.1371/journal.pcbi.1002005, 2011. P. Reitsma, B. Doiron & J.E. Rubin. Correlation transfer from basal ganglia to thalamus in Parkinson's disease. Frontiers in Computational Neuroscience 5:58 doi:10.3389/fncom.2011.00058, 2011. B. Doiron*, Y. Zhao* & T. Tzounopoulos. Combined LTP and LTD of Modulatory Inputs Controls Neuronal Processing of Primary Sensory Inputs. Journal of Neuroscience, 31:10579 –10592, 2011. S. B. P. Giridhar, B. Doiron & N.N. Urban. Timescale-dependent shaping of correlation by olfactory bulb lateral inhibition. Proceedings of the National Academy of Sciences, 108:5843-5848, 2011. M. Tabone, B. Ermentrout & Doiron B. Balancing Organization and Flexibility in Foraging Dynamics. Journal of Theoretical Biology, 266: 391-400, 2010. Y. Gai, B. Doiron & J. Rinzel. Slope based stochastic resonance: how noise enables phasic neurons to encode slow signals. PLoS Computational Biology 6, e1000825, 2010.


Y. Gai, B. Doiron, V. Kotak & J. Rinzel. Noise-gated Encoding of Slow Inputs by Auditory Brainstem Neurons With a Low Threshold K+ current. Journal of Neurophysiology 102: 3447–3460, 2009. K. Josic, E. Shea-Brown, B. Doiron & J. de la Rocha. Stimulus-Dependent Correlations and Population Codes. Neural Computation, 21: 2774–2804, 2009. A-M. M. Oswald*, B. Doiron*, J. Rinzel & A.D. Reyes. Spatial profile and differential recruitment of GABAB in inhibitory microcircuits modulate oscillatory activity in auditory cortex. Journal of Neuroscience, 29: 10321-10334, 2009. C. Ly & B. Doiron. Divisive Gain Modulation with Dynamic Stimuli in Integrate-and-Fire Neurons. PLoS Computational Biology 5, e1000365, 2009. C. Sutherland, B. Doiron & A. Longtin. Feedback-induced gain control in stochastic spiking networks. Biological Cybertics, 100: 475-489, 2009. B. Doiron. The role of variability in networks of spiking neurons, in Stochastic Neuroscience, editors C. Laing, G. Lord, Oxford University Press, 2009
W.H. Mehaffey, F.R. Fernandez, B. Doiron, L. Maler & R.W. Turner. Synaptic and Dynamic Regulation of Firing Dynamics by Backpropating Dendritic Spikes. Journal of Physiology (Paris) 102: 181-194, 2008. E. Shea-Brown, K. Josic, J. de la Rocha & B. Doiron. Correlation and Synchrony Transfer in Integrate-and-Fire Neurons: Basic Properties and Consequences for Coding. Physical Review Letters. 100, 108102, 2008. M. Day, B. Doiron & J. Rinzel. Stimulus-dependence of temporal encoding in an auditory brainstem neuron model. Journal of Neurophysiology 99: 534-544, 2008. N. Masuda & B. Doiron. Gamma Oscillations of spiking neural populations enhance signal discrimination. PLoS Computational Biology 3:2348-2355, 2007. J. de la Rocha*, B. Doiron*, E. Shea-Brown, K. Josic & A.D. Reyes. Correlation between neural spike trains increase with firing rate. Nature. 448: 802-806, 2007. B. Doiron, A-M.M. Oswald & L. Maler. Interval Coding II: Dendrite Dependent Mechanisms. Journal of Neurophysiology 97: 2744-2757, 2007. A-M. M. Oswald, B. Doiron & L. Maler. Interval Coding I: Burst Inter-Spike Intervals as Indicators of Stimulus Intensity. Journal of Neurophysiology 97: 2731 – 2743, 2007. S. Coombes*, B. Doiron*, E. Shea-Brown* & K. Josic*. Towards blueprints for network architecture, biophysical dynamics and signal transduction. Philosophical Transactions of the Royal Society A. 364:3301-3318, 2006. B. Doiron, J. Rinzel & A.D. Reyes. Stochastic synchronization in finite size spiking networks. Physical Review E (RC). 74: 030903, 2006. B. Lindner, B. Doiron & A. Longtin. Theory of oscillatory firing induced by spatially correlated noise and delayed inhibitory feedback. Physical Review E 72, 061919, 2005. W.H. Mehaffey, B. Doiron, L. Maler & R.W. Turner. Deterministic Multiplicative Gain Control with Active Dendrites. Journal of Neuroscience 25: 9968 – 9977, 2005. N. Masuda, B. Doiron, A. Longtin, K. Aihara. Coding of oscillatory signals by globally coupled networks of spiking neurons. Neural Computation 17:2139-75, 2005. C.R. Laing & B. Doiron. Ghostbursting: the role of Active Dendrites in Electrosensory Processing, in Bursting: The Genesis of Rhythm in the Nervous System, editors S. Coombes and P. C. Bressloff, World Scientific Press, 2005 Doiron B. Electrosensory Dynamics: Dendrites and Delays. Doctoral Dissertation. University of Ottawa, 2004 B. Doiron, B. Lindner, A. Longtin, L. Maler & J. Bastian. Oscillatory Activity in Electrosensory Neurons increases with the spatial correlation of the stochastic input stimulus. Physical Review Letters. 93:048101, 2004. A-M.M. Oswald, M.J. Chacron, B. Doiron, J. Bastian & L Maler. Parallel processing of sensory stimuli by bursts and isolated spikes. Journal of Neuroscience 24:4351-4362, 2004. M.J. Chacron, B. Doiron, L. Maler, A. Longtin & J. Bastain. Non-classical receptive field mediated biological switch in a sensory neuron’s frequency tuning. Nature 423, 77-81, 2003. C.R. Laing, B. Doiron, A. Longtin, L. Noonan, R.W. Turner & L. Maler. Type I Burst Excitability. Journal of Computational Neuroscience. 14:329-342, 2003. B. Doiron, M.J. Chacron, L. Maler, A. Longtin & J. Bastain. Inhibitory feedback required for network oscillatory responses to communication but not prey stimuli. Nature 421:539-543, 2003. L. Noonan*, B. Doiron*, C.R. Laing*, A. Longtin & R.W. Turner. A dynamic dendritic refractory period regulates burst discharge in the electrosensory lobe of weakly electric fish. Journal of Neuroscience 23: 1524-1534. 2003. B. Doiron, A. Longtin, Lindner B. Oscillatory network coding of a global stimulus, SPIE Proceedings, Fluctuations and Noise conference, Santa Fe, June 2003. B. Doiron, L. Noonan, N. Lemon, & R.W. Turner. Persistent Na+ current modifies burst discharge by regulating conditional backpropagation of dendritic spikes. Journal of Neurophysiology 89:338-354, 2003. R.W. Turner, N. Lemon, B. Doiron, R.J. Rashid, E. Morales, L. Maler, A. Longtin & R.J. Dunn. Oscillatory burst discharge generated through conditional backpropagtion of dendritic spikes. Journal of Physiology (Paris) 96:517-530, 2002. C.R. Laing, B. Doiron, A. Longtin & L. Maler. Ghostbursting: The effects of dendrites on spike patterns. Neurocomputing 44-46:127-132, 2002 A. Longtin, B. Doiron & A.R. Bulsara. Noise-induced divisive inhibition in simple neuronal models. Biosystems 67, 147-156, 2002. B. Doiron, C.R. Laing, A. Longtin & L. Maler. Ghostbursting: A novel neuronal burst mechanism. Journal of Computational Neuroscience 12:5-25, 2002. B. Doiron, A. Longtin, R.W. Turner & L. Maler. Model of gamma frequency burst discharge generated by conditional backpropagation. Journal of Neurophysiology 86: 1523-1545, 2001. B. Doiron, A. Longtin, N.J. Berman & L. Maler. Subtractive and divisive inhibition: Effect of voltage-dependent inhibitory conductances and noise. Neural Computation. 13: 227-248, 2001.
2015  G.K. Ocker, A Litwin-Kumar & B. Doiron. Self-organization of microcircuits in networks of spiking neurons with plastic synapses. PLoS Computational Biology, 11, e1004458, 2015.